Our research team aim to design and develop multiscale living materials for bio-interfaces to meet emerging needs in post-pandemics time, from the human-machine interface in telemedicine, biomedical therapy to sustainable agriculture. Living tissues are an integrated, multiscale architecture consisting of dense cell ensembles and extracellular matrices that cooperate to facilitate excellent self-organization, intercellular communication, and dynamic responsiveness. Our research is based on the hypothesis that a improved bio-interfaces with biological systems can be achieved by formulating “living” materials with adaptability, dynamic responsiveness, and self-regeneration. The living materials involves the integration of synthetic materials with living cells, or particles with biomimetic properties. The development of such biomaterials for improved bio-interfaces demands new design principles for integrating living and dynamically responsive components that interact at different length and time scales.
The design and engineering of adaptable, dynamically responsive, self-regenerative, and bio-integrative living materials (a grand challenge in material science research) will advance applications that interface with biological systems, such as telemedicine, biomedical therapy, and sustainable agriculture.